HOUSE DUST MITES SENSITIZATION ASSOCIATED WITH SOME ALLERGIC DISORDERS IN BENHA, EGYPT
Karim F. Abdallah1, Amany F. El Fakahany2, Amina I. Abd El-Maboud2, Sahar M. Aboul-khair3, Maysa A. Eraky2 and Gehan A. Rashed2
1Medical Parasitology Department, College of Medicine, Taif University, K.S.A
2Department of Parasitology, Faculty of Medicine, Benha University
3Department of Zoology, Faculty of Science, Benha University
One of the most important etiological factors of allergies was mites occurring in the closest vicinity of humans, i.e. in the house dust and in the stored foodstuffs. The aim of present study was to detect house dust mites sensitization among different types of allergic patients. A cross-sectional study was undertaken on 80 individuals, sixty cases suffering from different forms of allergy and 20 control individuals. Allergy was diagnosed by Skin prick test (SPT) using standard extracts of Dermatophagoides pteronyssinus, Dermatophagoides farinae. Serm samples were also examined to determine total IgE and specific IgE for house dust mites (HDM) mixed antigens. The total number of D. farinae sensitive cases was 21(26.5%) while the total number of D. pteronyssinus sensitive cases was 18(22.5%) with high significant difference between cases and controls. In the present study, (60%) of allergic rhinitis cases, (65%) of asthmatics, (75%) of atopic dermatitis cases and (5%) of controls were positive to HDM specific IgE. There was a significant correlation between total IgE and house dust mites mix specific IgE and there was high significant correlation between SPT results for both Dermatophagoids antigens and house dust mites mix specific IgE among the studied groups. There was no significant association between potentially supposed risk factors and allergy except patients with positive family history. Our results further confirm the association between HDM and allergy. Specific IgE assay for measurement of dust mite allergens demonstrated very good analytical characteristics for routine laboratory use.