EJMS

Abstract

Objectives: This retrospective study explored 43 files of patients who had intracranial meningioma (ICM) surgery in a trial to elucidate the ability to use perioperative data for the prediction of patients' outcomes. Patients & Methods: Patients' files were revised to extract the full perioperative patients, lesions, and operative data to be analyzed as independent variates for prediction of patients' outcomes as dependent variates for correlation, the Receiver Operating Characteristic (ROC) curve and Regression Analyses using the IBM® SPSS® Statistics software (Ver. 26, 2019; IBM Corporation; Armonk, USA). Results: The immediate postoperative (PO) complication rate was 58.1% including wound-related, general and psychiatric complications. During short-term follow-up, 8% and 9% of the presenting symptoms and signs deteriorated, 19.4% and 23% of manifestations were unchanged and 72.6% and 68% were improved. PO seizures and speech disorders were reported in 7% of patients. During long-term follow-up, the ICM recurrence rate was 11.6% and the mortality rate was 4.7%. Statistical analyses showed that old age and obesity in male patients could predict a high mortality rate. Also, the more frequent and severe preoperative medical disorders; the higher the mortality rate. Prolonged operative time and difficult lesions' debulking might predict incomplete debulking. Incomplete debulking of the ICM was the major predictor for deterioration of clinical manifestations and higher recurrence rates. Conclusion: Old age, the preoperative presence of medical disorders, incomplete debulking of the ICM and prolonged duration of surgery are independent predictors for poor PO outcomes, especially as regards deterioration of preoperative manifestations and mortality. Incomplete debulking of ICM is the main predictor for its recurrence.